Omega-3 fatty acids, CoQ10, and berry concentrate rich in antioxidants have all shown independent benefit for cardiovascular health, through overlapping as well as unique mechanisms. Berry intake has been shown to induce favorable changes in platelet function, HDL cholesterol, and blood pressure, and polyphenol and flavonoid intake has been associated with reduced risk of death due to coronary heart disease, cardiovascular disease, as well as all-cause mortality. DHA and EPA from fish oil have broad cardiovascular benefit, and have been shown to lower atherosclerotic burden, reduce triglyceride levels and blood pressure, and improve platelet and vascular function. In clinical trials, omega-3 fatty acids from fish oil have reduced rates of all-cause mortality, cardiac and sudden death, as well as stroke. CoQ10 supports cardiovascular health by improving endothelial function, reducing atherosclerosis, lowering blood pressure, and improving ventricular contractility. In clinical trials, CoQ10 has shown benefit for a wide range of cardiovascular conditions, including congestive heart failure, hypertension, and prevention of myocardial infarction. Together, these complementary nutrients reduce oxidative damage, inhibit inflammatory processes, and improve vascular function.

Serving Size: 1 softgel
Servings per Container: 60

1 Softgel Provides:
Calories....................................................................................................... 10 
   Calories from Fat...................................................................................... 10
Total Fat....................................................................................................... 1 g
Cholesterol.................................................................................................... 5 mg
Fish Oil Concentrate (Molecularly Distilled, Ultra-Purified)......................... 834 mg 
   (Anchovy, sardine and/or mackerel) 
   Omega-3 Fatty Acids............................................................................. 450 mg 
      Eicosapentaenoic Acid (EPA).............................................................. 300 mg 
      Docosahexaenoic Acid (DHA)............................................................. 150 mg
Coenzyme Q10.......................................................................................... 100 mg
BerryRich^TM Proprietary Blend ORAC value 300........................................ 50 mg 
   (Grape, Pomegranate, Strawberry, Cranberry, Blueberry, Raspberry & Bilberry)

Other Ingredients: Softgel capsule (gelatin, purified water, glycerin, caramel), yellow beeswax, soy lecithin.

1 softgel, 2 times per day or as directed by a health care professional.

Individuals with an allergy to fish or seafood should use caution, though fish oil is rarely allergenic. Both benefit and risk has been documented for those at risk of or being treated for cardiac arrhythmias, with close supervision indicated. Pregnant and nursing women are often advised to consume DHA, but although DHA is recognized as essential to neurological development, no dosage recommendations have been made for children or infants.
 
No specific contraindications exist or are predicted, but data is lacking for CoQ10 use during pregnancy, lactation, and in children, and the dosage may need to be reduced for those less than 18.

Drug Interactions: The antihypertensive effect of fish oil may potentially reduce the need or dosage for blood pressure medications, and patients should be closely monitored. Because fish oil has an antithrombotic effect, caution is advised for those on anticlotting, antiplatelet, or anticoagulant medications, or those at high risk of bleeding. At doses greater than 3 g per day, hyperglycemia has been observed in diabetics and those with hypertriglyceridemia, and close monitoring of patients on antidiabetic medication is recommended.
 
To prevent side effects or the depletion of CoQ10 in body tissues, many health experts recommend supplementing CoQ10 at dosages ranging from 30 to 400 mg per day in people taking the following drugs:

• Cholesterol lowering drugs, such as atorvastatin (Lipitor); gemfibrozil (Lopid); lovastatin (Mevacor); pravastatin (Pravachol); simvastatin (Zocor), etc.
• Beta-blocker drugs used in angina, high blood pressure, and heart arrhythmias, such as acebutolol (Sectral); atenolol (Tenormin); carteolol (Cartrol); metoprolol (Lopressor, Toprol XL); penbutolol (Levatol); propanolol (Inderal); timolol (Blocarden), etc.
• Phenothiazine drugs used in various psychiatric disorders such as chlorpromazine (Thorazine); fluphenazine (Permitil, Prolixin); mesoridazine (Serentil); trifluoperazine (Stelazine); etc.
• Tricyclic antidepressants, such as amitryptaline (Elavil, Endep); desipramine (Norpramin, Pertofrane); doxepin (Adapin, Sinequan); imipramine (Imavate, Presamine, Trofinil); nortryptaline (Aventyl, Pamelor); protryptaline (Vivactil); etc.

Product contains no: artificial preservatives or sweeteners; no dairy, gluten or wheat.